• According to the World Federation of Hemophilia, Brazil has, in absolute numbers, the third largest population of patients with hemophilia.  As such, in December of 2018, AHF convened a workshop on hemophilia in São Paulo entitled “Workshop: Updating Public Policy on Early Diagnosis and Optimal Treatment of Hemophilia in Brazil.” Dr.
  • An estimated 1.1 million men worldwide were diagnosed with prostate cancer in 2012, accounting for 15% of the cancers diagnosed in men. Prostate cancer is the most common cancer among men (after skin cancer), but it can often be treated successfully. The prostate gland makes fluid that forms part of the semen. The prostate lies just below the bladder and surrounds the urethra. Almost all prostate cancers are adenocarcinomas, which are cancers developed from the gland cells, which make the prostate fluid.
  • Hereditary Breast and Ovarian Cancer (HBOC) syndrome is a genetic condition that can be inherited through either the maternal or paternal carrier. Most families affected by this condition have mutations within the genes BRCA1 (breast cancer 1, early onset) and BRCA2 (breast cancer 2). Genetic testing and genetic counselling are essential components to both prevention and treatment, assessing patient’s risk factors for HBOC syndrome and determining the best method of care. With screening and appropriate prevention methods, smaller, more curable cancers are detected and treated sooner.
  • In celebration of World Osteoporosis Day on October 20th, the Americas Health Foundation (AHF) announces the publication of a consensus statement produced by an expert panel on osteoporosis. The panel concludes that osteoporosis should be considered a public health priority in Latin America given its enormous health impact on patients and financial impact on health care systems and the economy.
  • Therapeutic advance in oncology treatments are due in part to a more complete understanding of its genomic portrait. The serial monitoring of tumor genotypes, which are instable and prone to changes under selective pressure, is becoming increasingly needed. Although tumor biopsies remain the reference standard for the diagnosis and genotyping of many types of cancer, they are invasive and not always feasible.
  • Next  generation  sequencing  (NGS),  also  known  as  high-throughput  sequencing,  describes  a  DNA  sequencing  technology  that  has  revolutionized  genomic  research  by  allowing  an  entire  human  genome  to  be  sequenced  within  a  single  day.  In  contrast,  the  previous  sequencing  technology  required  over  a  decade  to  deliver  the  final  draft.  NGS  can  be  used  to  sequence  entire  genomes  or  can  be  constrained  to  specific  areas  of  interest,  including  all  22,000  coding  genes  or  small  numbers  of  individual  genes.  There  are  numerous  opport
  • In February, AHF attended the Sanford Rare Disease Symposium hosted by Sanford Research and the Coordination of Rare Diseases at Sanford (CoRDS) to raise awareness of the importance of rare disease research and provide information to scientists and healthcare providers. The CoRDS registry, established in 2010, is a centralized international patient registry for all rare diseases that aims to connect as many patients and researchers as possible to help advance treatments and cures for rare diseases. 
  • Osteoporosis is a disease in which the density and quality of bone are reduced, leading to weakness of the skeleton and increased risk of fracture, particularly of the spine, wrist, hip, pelvis and upper arm. Osteoporosis and associated fractures are an important cause of mortality and morbidity and primarily affect postmenopausal women and elderly men.
  • With more than 50 million cases reported to the World Health Organization (WHO) each year, dengue is now regarded as the world’s most important mosquito-borne viral disease. Moreover, given that 60% of these reports are from the Americas, predominantly Latin America, dengue infection is a significant and escalating public health problem in Latin America.