• Using ctDNA as a liquid biopsy may herald a revolution for tumor management. In the era of personalized medicine, liquid biopsies represent the turning point in cancer management. Furthermore, KRAS testing has a potentially bright future in the area of oncology for tumor diagnosis and appropriate treatment decisions. KRAS mutation analysis is ordered primarily to determine if metastatic colon cancer or non-small cell lung cancer is likely to respond to standard therapy, an anti-EGFR drug therapy. Tumors with the KRAS mutation do not respond to anti-EGFR therapy.
  • Asthma has a broad range frequency and severity. This condition can be classified into four main categories: (1) intermittent, (2) mild persistent, (3) moderate persistent and (4) severe persistent. Severe persistent asthma is often uncontrolled and has many different symptoms including coughing, wheezing, chest tightness or difficulty breathing that are continual, frequent nighttime symptoms, lung function test FEV1 60% or less of normal values, and peak flow more than 30% variability.
  • Breast cancer remains the most prevalent cancer in the world. Much progress has been made in the diagnosis, management and outcomes of early breast cancer, however major gaps still exist in the treatment and management of advanced breast cancer (ABC) and median survival has remained stubbornly stuck at two to three years after diagnosis, with 50% of cases and 58% of deaths occurring in less developed countries. ABC is an umbrella term for both locally advanced breast cancer (stage 3) and metastatic breast cancer (stage 4).
  • In September of 2019, different aspects of NGS of ctDNA through solid biopsy and its application for NSCLC were discussed during a one-day meeting with a full panel comprised of 5 experts from Brazil. Panel members included Dr. Gilberto Castro, Dra. Renata Coudry, Dra. Clarissa Baldotto, and Dra. Clarissa Mathias. The panel was moderated by Dr. Luiz Henrique Araujo.
  • Similar to other non-communicable diseases in Turkey, one in every seven women aged 50 years will endure a hip fracture in the remainder of their life. In 2010, a country-wide study estimated the number of hip fractures to reach 24,000 and forecasted hip fractures to more than double throughout the subsequent 25 years. While this study showed the prevalence of hip fractures, they were unable to directly link it to osteoporosis (only to lack of activity).
  • According to the World Federation of Hemophilia, Brazil has, in absolute numbers, the third largest population of patients with hemophilia.  As such, in December of 2018, AHF convened a workshop on hemophilia in São Paulo entitled “Workshop: Updating Public Policy on Early Diagnosis and Optimal Treatment of Hemophilia in Brazil.” Dr.
  • An estimated 1.1 million men worldwide were diagnosed with prostate cancer in 2012, accounting for 15% of the cancers diagnosed in men. Prostate cancer is the most common cancer among men (after skin cancer), but it can often be treated successfully. The prostate gland makes fluid that forms part of the semen. The prostate lies just below the bladder and surrounds the urethra. Almost all prostate cancers are adenocarcinomas, which are cancers developed from the gland cells, which make the prostate fluid.
  • Hereditary Breast and Ovarian Cancer (HBOC) syndrome is a genetic condition that can be inherited through either the maternal or paternal carrier. Most families affected by this condition have mutations within the genes BRCA1 (breast cancer 1, early onset) and BRCA2 (breast cancer 2). Genetic testing and genetic counselling are essential components to both prevention and treatment, assessing patient’s risk factors for HBOC syndrome and determining the best method of care. With screening and appropriate prevention methods, smaller, more curable cancers are detected and treated sooner.
  • In celebration of World Osteoporosis Day on October 20th, the Americas Health Foundation (AHF) announces the publication of a consensus statement produced by an expert panel on osteoporosis. The panel concludes that osteoporosis should be considered a public health priority in Latin America given its enormous health impact on patients and financial impact on health care systems and the economy.